Cape Verde are the biggest overall movers in the latest Fifa World Rankings as they climbed a total of 47 places.
The Blue Sharks' two victories over South Africa in 2018 World Cup qualifying has seen them move from 114 to 67 globally and 13th in Africa.
Despite falling five places overall, Egypt are still the highest-ranked nation on the continent.
The Pharaohs are just one place ahead of North African rivals Tunisia.
Tunisia replace DR Congo as the second-ranked side in Africa after the Carthage Eagles beat the Leopards and drew with them in the World Cup qualifiers.
DR Congo fall 14 places globally and down to fourth on the continent behind third-placed Senegal.
Germany have returned to the number one side in the world, ahead of Brazil.
Africa's top ten on September's Fifa rankings - global ranking in brackets:
01. Egypt (30)
02. Tunisia (31)
03. Senegal (33)
04. DR Congo (42)
05. Nigeria (44)
06. Cameroon (45)
07. Burkina Faso (49)
08. Ghana (52)
09. Ivory Coast (54)
10. Morocco (56)
